Background: The coexistence of hypercoagulability and bleeding diathesis in the same patient represents a potentially lethal combination due to its complex management.Vascular Ehlers-Danlos syndrome (vEDS) and sticky platelet syndrome (SPS) are classified as rare diseases due to their BEETS low prevalence.vEDS is associated with bleeding tendencies
Gastroesophageal Reflux Disease: Medical or Surgical Treatment?
Background.Gastroesophageal reflux disease is a common condition with increasing prevalence worldwide.The disease encompasses a broad spectrum of clinical symptoms and disorders from simple heartburn without esophagitis to erosive esophagitis with severe complications, such as esophageal strictures and intestinal metaplasia.Diagnosis is based mainl
Impact of digital stress on negative emotions and physical complaints in the home office: a follow up study
ABSTRACTBackground Due to the COVID-19 pandemic many employees perform under increasingly digital conditions.Enabling home office environments became mandatory for companies wherever possible in consideration of the ongoing pandemic.Simultaneously, studies reported on digital stress.The current literature lacks rigorous research into digital stress
Probing the functional mechanism of Escherichia coli GroEL using circular permutation.
BACKGROUND: The Escherichia coli chaperonin GroEL subunit consists of three domains linked via two hinge regions, and each domain is responsible for a specific role in the functional mechanism.Here, we have used circular permutation to study the structural and functional characteristics of the GroEL subunit.METHODOLOGY/PRINCIPAL FINDINGS: Three sol
Challenges of Implementing Circular Economy in Polluting Industries: A Hybrid Meta-synthesis and Fuzzy DEMATEL-ANP Approach
The present study sought to provide a pattern of the relationships among the challenges of implementing a circular economy in polluting industries.In terms of purpose, this research is considered as a component of applied developmental research and regarding research type, it is considered as a mix method (exploratory mix) one.Yazd glass industry w